NETRIN-1 CONFINES RHOMBIC LIP-DERIVED NEURONS TO THE CNS

Netrin-1 Confines Rhombic Lip-Derived Neurons to the CNS

Summary: During brainstem development, newborn neurons originating from the rhombic lip embark on exceptionally long migrations to generate nuclei important for audition, movement, and respiration.Along the way, this highly motile population passes several cranial nerves yet remains confined to the CNS.We found that Ntn1 accumulates beneath the pia

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A Two-Piece Derivative of a Group I Intron RNA as a Platform for Designing Self-Assembling RNA Templates to Promote Peptide Ligation

Multicomponent RNA-peptide complexes are attractive from the viewpoint of artificial design of functional biomacromolecular systems.We have developed self-folding and self-assembling RNAs that serve as templates to Glitter Coffee Mug assist chemical ligation between two reactive peptides with RNA-binding capabilities.The design principle of previou

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Diagnosis and treatment of intractable idiopathic orofacial pain with attention-deficit/hyperactivity disorder

Abstract Attention-deficit/hyperactivity disorder (ADHD) has been reported to be associated with primary chronic pain syndromes, such as fibromyalgia, migraine, and Toys chronic low back pain.Although idiopathic orofacial pain (IOP) is classified as burning mouth syndrome or persistent idiopathic facial or dentoalveolar pain and as a primary chroni

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Exploring the Utility of 3-D-printed Laboratory Equipment

Many laboratories utilize different types of opto-mechanical positioning devices in their experiments.Such devices include lateral stages, which provide 1-dimenstional translational movement, 3-dimensional translation stages, and laboratory jacks, which provide a convenient way of changing the vertical position of a sample.Recent advances in and af

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